When creating your campaign, you can select a particular area to include or exclude using targeting types. If you don't wish to narrow your focus, the entire United States will be included, as shown here:
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We use real-time data points on viewers to determine the geographic location of the streaming content your video ads will run within. Marketers can use this same data to ensure your ad campaigns are being shown to customers within the geographic regions that matter most.

To define your location targeting, click edit on the “Locations” panel.

A window will open where you can choose a targeting type to include or exclude specific geographic locations.
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We offer 3 types to choose from:

Note: If a special category is declared (i.e. Credit, Housing, or Employment) at the campaign or creative level, zip-code targeting will not be selectable.

Note: Political ad accounts will also have access to Congressional District targeting, which bundles zip-codes together by congressional district.

You can only include or exclude locations using 1 geographic type (states, ZIP Codes, or market areas). For example, you can include and exclude audiences in the states of New York AND New Jersey because they're both states. You can't target the state of New York AND ZIP Codes in New Jersey because they're different types of locations. Your selections are automatically saved and applied to your campaign.

Whichever type you choose, your ad will only be shown to viewers in those particular states, ZIP Codes, or market areas.

Your ads will deliver across the United States but won't be shown in the states, ZIP Codes, or market areas you select.

If you need to mix location targeting types, try creating separate inclusion and exclusion audiences, each using a different location type. For example, you may include the New York marketing area but exclude the state of New Jersey (or a handful of ZIP Codes in New Jersey).